Unraveling Familial Mediterranean Fever A Quest for Answers

Familial Mediterranean fever is a rare genetic disease that often first appears in childhood as recurring fevers. It is a rare, inherited disorder, the most common disorder in a family of related “auto‐inflammatory” disorders, which are characterized by an ... Familial Mediterranean fever (FMF) is a hereditary inflammatory condition. It mostly affects people of Mediterranean origin. FMF is a non-infectious genetic disorder manifested by episodic fevers typically accompanied by pain in the abdomen, joints, or chest. Familial Mediterranean fever (FMF) is a rare disorder passed down through families (inherited). It involves repeated fevers and inflammation that often affects ... Familial Mediterranean fever is a rare autoinflammatory disease in which the body causes inflammation "on its own". Familial Mediterranean fever (FMF) is the most common monogenic autoinflammatory disease, but many rheumatologists are not well acquainted with its management. Anakinra is a recombinant human IL-1 receptor antagonist that inhibits binding of IL-1 to its receptor, and thereby prevents IL-1-mediated inflammation. A typical attack consists of fever and serositis lasting from 1 to 4 days. Between attacks, FMF patients are free of symptoms and appear healthy. The frequency ... Background Information · inherited autosomal recessive inflammatory disorder · mutations in Mediterranean Fever (MEFV) gene, located on short ...